Group Publications

11.  Ody, B. K.; Zhang, J.; Nelson, S. E.; Xie, Y.; Liu, R.; Dodd, C. J.; Jacobs, S. E.; Whitzel, S. L.; Williams, L. A.; Gozem, S.; Turlington, M.; Yin, J. Synthesis and Evaluation of Cereblon-Recruiting HaloPROTACs. ChemBioChem 2023, 24 (21), e202300498.

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10. Lester, A.; Sandman, M.; Herring, C.; Girard, C.; Dixon, B.; Ramsdell, H.; Reber, C.; Poulos, J.; Mitchell, A.; Spinney, A.; Henager, M. E.; Evans, C. N.; Turlington, M.; Johnson, Q. R. Computational Exploration of Potential CFTR Binding Sites for Type I Corrector Drugs. Biochemistry 2023, 62 (16), 2503–2515.

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9. Ramey, E. E.; Whitman, E. ; Buller, C. E.; Tucker, J. R.; Jolly, C. S.; Oberle, K. G.; Becksvoort, A. J.; Turlington, M.; Turlington, C. R. A Biodegradable, Polymer-Supported Oxygen Atom Transfer Reagent. Polymers 2023, 15 (9), 2052.

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8. Oberle, K. G.; Whitman, E. L.; Jolly, C. S.; Webster, K. A.; Marx, B. S.; Howard, C. M.; Hanger, C. A.; Ramey, E. E.; Zou, Y.; Lowe, J. C.; Turlington, M.; Turlington C. R. Metallopolymers in minutes via organocatalysis at room temperature. Polym. Chem. 2022, 13, 4747-4751.

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7.  Jolly, C. S.; Kochanowski, E.; Dodd, C. J.; Post, S. J.; Hill, H. M.; Turlington, M. Diastereoselective Synthesis of Terminal Bromo-Substituted Propargylamines via Generation of Lithium Bromoacetylide and Addition to Chiral N-Tert-Butanesulfinyl Aldimines. J. Org. Chem. 2021, 86 (3), 2667–2681. https://doi.org/10.1021/acs.joc.0c02697.

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6. Doiron, J. E.; Le, C. A.; Bacsa, J.; Breton, G. W.; Martin, K. L.; Aller, S. G.; Turlington, M. Structural Consequences of the 1,2,3-Triazole as an Amide Bioisostere in Analogues of the Cystic Fibrosis Drugs VX-809 and VX-770. ChemMedChem 2020, 15 (18), 1720–1730. https://doi.org/10.1002/cmdc.202000220.

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5. Doiron, J. E.; Le, C. A.; Ody, B. K.; Brace, J. B.; Post, S. J.; Thacker, N. L.; Hill, H. M.; Breton, G. W.; Mulder, M. J.; Chang, S.; Bridges, T. M.; Tang, L.; Wang, W.; Rowe, S. M.; Aller, S. G.; Turlington, M. Evaluation of 1,2,3-Triazoles as Amide Bioisosteres In Cystic Fibrosis Transmembrane Conductance Regulator Modulators VX-770 and VX-809. Chem. Eur. J. 2019, 25, 3662-3674. DOI: 10.1002/chem.201805919

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4. Prince, C. E.; Turlington, M. Nitration of 2-tert-Butylaniline: Preparation of an Intermediate Used in the Development of the Cystic Fibrosis Drug Ivacaftor. Chem. Educator  2018, 23, 124-128.

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3.  Penk, D. N.; Robinson, N. A.; Hill, H. M.; Turlington, M.  “A flexible method for the synthesis of 2-substituted 1,2,5,6-tetrahydropyridines and piperidines from chloro-containing propargylamines.” Tetrahedron Lett. 2017, 58, 470-473.

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2. Jordan, S.; Starks, S. A.; Whatley, M. F.; Turlington, M. “Highly Stereoselective Synthesis of Terminal Chloro-Substituted Propargylamines and Further Functionalization.” Org.  Lett. 2015, 17, 4842-4845.

alkyne scheme

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1. Breton, G. W.; Turlington, M. “Alternative synthetic routes to N-methyl-1,2,4-triazoline-3,5-dione (MeTAD) and other triazolinedione derivatives.”  Tetrahedron Lett. 2014, 55, 4661-4663.

urazole toc

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